Table 2.

LGI3 immunohistochemical staining of vitiligo patients before and after phototherapy, and controls

Immunohistochemical staining	Studied group (N=60)						Test of Significance	p-value
	Controls n=20		Cases before treatment n=40		Cases after treatment n=40
Expression	NO	%	NO	%	NO	%	T1=χ2=8.29	P1=0.003*
Positive	20	100	27	67.5	37	92.5	T2=Mc Nemar χ2=10.58	P2=0.001*
Negative	0	0.0	13	32.5	3	7.5	T3= χ2=1.85	P3=0.554
Localization
Cytoplasmic	18	90	24	88.9	31	83.8	T1= χ2=0.83	P1=0.659
Membranous	0	0	1	3.7	1	2.7	T2=MH=0.447	P2=0.655
Membrano-cytoplasmic	2	10	2	7.4	5	13.5	T3= χ2=0.73	P3=0.694
Intensity
Mild	10	50.0	22	81.5	18	48.6	T1= χ2=8.65	P1=0.013*
Moderate	5	25.0	5	18.5	14	37.8	T2=MH=2.99	P2=0.003*
Strong	5	25.0	0	0.0	5	13.5	T3= χ21.62	P3=0.444
Distribution							T1= χ2=0.366	P1=0.545
Patchy	14	70.0	21	77.8	20	54.05	T2=Mc Nemar χ2=6.50	P2=0.011*
Diffuse	6	30.0	6	22.2	17	45.9	T3= χ2=1.37	P3=0.242
Percentage
Mean ± SD	40.25±26.83		18.22±18.44		39.07±24.89		T1=U=116.00	P1=0.001*
Range	10.0-85.0		2.0-70.0		2.0-95.0		T2=Wilcoxon signed rank=4.29	P2=0.001*
Median	30.0		10.0		30.0		T3=U=0.528	P3=0.597
H score
Mean ± SD	89.75±94.79		25.26±31.03		74.11±71.96		T1=U=3.39	P1=0.001*
Range	10.0-255.0		2.0-120.0		2.0-240.0		T2=Wilcoxon signed rank =4.38	P2=0.001*
Median	40.0		10.0		45.0		T3=U=0.570	P3=0.569

T1: test of significance for comparison between cases before treatment and controls; T2: test of significance for comparison between cases before and after treatment; T3: test of significance for comparison between cases after treatment and controls; P1: p-value of comparison between cases before treatment and controls; P2: p-value of comparison between cases before and after treatment; P3: p-value of comparison between cases after treatment and controls;

^*Significant.