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. Author manuscript; available in PMC: 2021 Jan 3.
Published in final edited form as: Adv Funct Mater. 2019 Nov 8;30(1):10.1002/adfm.201906237. doi: 10.1002/adfm.201906237

Figure 4.

Figure 4.

(a) SLA 3D printed PEGDA hydrogel multiple channel nerve guides with cuff for implantation, and (b) their regenerated axon count against a control (uninjured) tissue. Reproduced with permission.[152] Copyright 2015, Thieme Medical Publishers. (c) Fibrin/HA scaffold containing encapsulated Schwann cells via a one-pot printing process. (d) Phase contrast and fluorescence images of printed Schwann cells in a 200 μm width channel. Reproduced with permission.[112] Copyright 2017, Elsevier. (e-h) Extrusion-based 3D printing of a bifurcated silicone nerve guide functionalized with physical cues and path-specific biochemical gradients. (e) Bifurcation pathways in the sciatic nerve which contain branches of sensory and motor nerves, (f) transected nerve pathway, (g) printed NGF gradient for sensory path cues and GDNF gradient for motor path cues in the scaffold, and (h) an implanted 3D printed nerve scaffold. Reproduced with permission.[17] Copyright 2015, Wiley-VCH.