Table 1. Cluster and cooperative channel parameters.

$N$: number of clusters, $S$: cluster size, $J$: overall coupling, $j$: channel-channel coupling, $V_{0.5}$: half activation, $k$: width of the channel activation, $\tau$: time constant of the channel with maximum at attained at $V_m$ and width $\sigma$, $g_{coop}$: single channel conductance and $E_{coop}$: reversal potential.

Figure	$N$	$S$	$J$	$j$	$V_{0.5}$	k	$\tau$	$V_m$	$\sigma$	gcoop	Ecoop
			mV	mV	mV	mV	ms	mV	mV	pS	mV
Figure 1 (independent)	1	6	0	0	−1	15	0.5	−1	30	-	-
Figure 1 (weak coop.)	1	6	22.5	4.5	−1	15	0.5	−1	30	-	-
Figure 1 (strong coop.)	1	6	70	14	−1	15	0.5	−1	30	-	-
Figure 2 (independent)	1	6	0	0	−1	15	0.5	−1	30	-	-
Figure 2 (cooperative)	1	6	100	20	−1	15	0.5	−1	30	-	-
Figure 3	1	5	100	25	−1	15	0.5	−1	30	-	-
Figure 4	100	8	80	11.4	−30	10	120	−30	20	2.5	100
Figure 5	100	8	80	11.4	−30	10	120	−30	20	2.5	100
Figure 6c	90	8	101.5	14.5	−10	15	100	−10	30	1	100
Figure 3—figure supplement 1	1	5	100	25	−1	15	0.5	−1	30	-	-
Figure 4—figure supplement 1A	100	8	80	11.4	−30	10	120	−30	20	2.5	100
Figure 4—figure supplement 1B	100	8	80	11.4	−30	10	120	−30	20	10	−100
Figure 4—figure supplement 2	100	8	80	11.4	−30	10	120	−30	20	2.5	100
Figure 5—figure supplement 1A,B	100	8	80	11.4	−30	10	10–240	−30	20	2.5	100
Figure 5—figure supplement 1C,D	100	8	80	11.4	−30	10	120	−30	20	0.5–10	100
Figure 6—figure supplement 1 (independent channels, red)	90	8	0	0	−10	15	100	−10	30	1	100
Figure 6—figure supplement 1 (cooperative channels, black)	90	8	101.5	14.5	−10	15	100	−10	30	1	100