Table 1. Expression and methylation of SMPD3 in patient-matched dysplasia and CIS/OSCC samples.
Dysplasia | CIS/OSCC | |
---|---|---|
Hypermethylateda | 6 | 10 |
Downregulatedb | 5 | 6 |
Hypermethylated and downregulated in the same patient | 4 | 6 |
aΔβ-value of ≥0.15 compared with adjacent normal tissue in at least one CpG within the SMPD3 promoter. bFold-change of ≥2 compared with adjacent normal tissue in at least one SMPD3 probe. N = 10.