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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Xenotransplantation. 2019 Sep 23;27(1):e12552. doi: 10.1111/xen.12552

Figure 1:

Figure 1:

Tg expression assessed by FCM. (A-D) X-axis demonstrates hCD55 and Y–axis demonstrates hCD47. (E, F) X-axis demonstrates HLA-E and Y-axis demonstrates hCD46. A: PBMC of GalTKO. B: PBMC of hCD55 Tg Sachs GalTKO pig, C: PBMC of hCD47/hCD55 Tg pig, D: BM of hCD47/hCD55 Tg Sachs GalTKO pig. In hCD47/hCD55 Tg pig PBMC and BM, both Tg were well expressed, whereas hCD47 expression was absent in Sachs GalTKO and hCD55 GalTKO pigs. E: PBMC of GalTKO pig, F: PBMC of hCD46/HLA-E Tg Revivicor pig, G: BM of hCD46/HLA-E Tg Revivicor pig. The expression of HLA-E was weak in BM cells. BM: bone marrow, FCM: flow cytometry, h: human, HLA: human leukocyte antigen, PBMC: peripheral blood mononuclear cell, Tg: transgene.