Table 1.
Characteristics of SLK Recipients.
| HCV negative recipients (N = 3786) | HCV positive recipients (N = 2428) | |||||
|---|---|---|---|---|---|---|
| No DGF | DGF | p-value | No DGF | DGF | p-value | |
| N = 2935 | N = 851 | N = 1926 | N = 502 | |||
| Recipient characteristics | ||||||
| Age at transplant, median (IQR) | 57 (48, 63) | 56 (46, 62) | 0.003 | 56 (52, 61) | 58 (52, 61) | 0.01 |
| Female | 1150 (39.2%) | 359 (42.2%) | 0.1 | 493 (25.6%) | 140 (27.9%) | 0.3 |
| Race | 0.04 | 0.01 | ||||
| White | 2062 (70.3%) | 558 (65.6%) | 1053 (54.7%) | 248 (49.4%) | ||
| Black | 296 (10.1%) | 91 (10.7%) | 473 (24.6%) | 115 (22.9%) | ||
| Other | 577 (19.7%) | 202 (23.7%) | 400 (20.8%) | 139 (27.7%) | ||
| Hospitalization pretransplant | 885 (39.5%) | 299 (50.7%) | <0.001 | 578 (35.9%) | 205 (53.4%) | <0.001 |
| MELD at transplant, median (IQR) | 30 (24, 36) | 33 (26, 39) | <0.001 | 28 (23, 35) | 33 (25, 39) | <0.001 |
| Dialysis pretransplant | <0.001 | <0.001 | ||||
| Any | 1778 (60.6%) | 709 (83.3%) | 1161 (60.3%) | 414 (82.5%) | ||
| < 6 weeks dialysis | 602 (20.5%) | 245 (28.8%) | 339 (17.6%) | 132 (26.3%) | ||
| ≥ 6 weeks dialysis | 1176 (40.1%) | 464 (54.5%) | 822 (42.7%) | 282 (56.2%) | ||
| Years on dialysis, median (IQR) | 0.1 (0.0, 0.4) | 0.1 (0.03, 0.8) | <0.001 | 0.1 (0.0, 0.8) | 0.2 (0.03, 1.5) | <0.001 |
| Previous kidney transplantation | 130 (4.4%) | 42 (4.9%) | 0.5 | 113 (5.9%) | 31 (6.2%) | 0.8 |
| Previous liver transplantation | 325 (11.1%) | 87 (10.2%) | 0.5 | 258 (13.4%) | 70 (13.9%) | 0.8 |
| Donor characteristics | ||||||
| Age at procurement, median (IQR) | 33 (22, 47) | 40 (27, 50) | <0.001 | 33 (23, 46) | 40 (26, 50) | <0.001 |
| Female | 1140 (38.8%) | 357 (42.0%) | 0.1 | 727 (37.7%) | 200 (39.8%) | 0.4 |
| Race | 0.1 | 0.01 | ||||
| White | 1938 (66.0%) | 560 (65.8%) | 1284 (66.7%) | 301 (60.0%) | ||
| Black | 491 (16.7%) | 123 (14.5%) | 307 (15.9%) | 80 (15.9%) | ||
| Other | 506 (17.3%) | 168 (19.7%) | 335 (17.4%) | 121 (24.1) | ||
| BMI, median (IQR) | 25 (22, 29) | 27 (23, 31) | <0.001 | 25 (23, 29) | 26 (23, 30) | 0.004 |
| Creatinine, median (IQR) | 0.9 (0.7, 1.2) | 1.0 (0.7, 1.3) | 0.01 | 0.9 (0.7, 1.2) | 1.0 (0.7, 1.3) | 0.02 |
| History of hypertension | 534 (18.3%) | 243 (29.0%) | <0.001 | 372 (19.4%) | 133 (26.9%) | <0.001 |
| History of diabetes mellitus | 108 (3.7%) | 58 (6.9%) | <0.001 | 65 (3.4%) | 32 (6.5%) | 0.003 |
| HLA mismatches, median (IQR) | 5 (4, 5) | 5 (4, 5) | 0.95 | 5 (4, 6) | 5 (4, 5) | 0.03 |
| Organ share type | <0.001 | 0.03 | ||||
| Local | 2423 (82.6%) | 606 (71.2%) | 1560 (81.0%) | 383 (76.3%) | ||
| Regional | 487 (16.6%) | 233 (27.4%) | 319 (16.6%) | 98 (19.5%) | ||
| National | 25 (0.9%) | 12 (1.4%) | 47 (2.4%) | 21 (4.2%) | ||
| DCD donor | 98 (3.3%) | 62 (7.3%) | <0.001 | 59 (3.1%) | 26 (5.2%) | 0.03 |
| KDPI, median (IQR) | 29 (12, 52) | 41 (19, 63) | <0.001 | 33 (14, 54) | 43 (24, 65) | <0.001 |
| DRI, median (IQR) | 1.2 (1.1, 1.4) | 1.3 (1.1, 1.6) | <0.001 | 1.2 (1.1, 1.) | 1.3 (1.1, 1.6) | <0.001 |
| Kidney on machine perfusion | 617 (21.0%) | 147 (17.3%) | 0.02 | 333 (17.3%) | 72 (14.3%) | 0.1 |
| Transplant characteristics | ||||||
| Kidney CIT, hours, median (IQR) | 10 (8, 13) | 11 (9, 15) | <0.001 | 10 (8, 13) | 11 (9, 15) | <0.001 |
| Liver CIT, hours, median (IQR) | 6 (5, 8) | 7 (5, 8) | <0.001 | 6 (5, 8) | 7 (5, 8) | <0.001 |
| Use of induction immunosuppression | 2345 (79.9%) | 722 (84.8%) | 0.001 | 1543 (80.1%) | 412 (82.1%) | 0.3 |
| Transplant year, median (IQR) | 2011 (2007, 2014) | 2012 (2008, 2015) | <0.001 | 2010 (2006, 2014) | 2012 (2008, 2014) | <0.001 |