Table 4.
Risk Factors for mortality and graft failure in SLK recipients.
| Adjusted Hazard Ratio (95% CI, p-value) | |||
|---|---|---|---|
| Mortality | Kidney Graft Failure | Liver Graft Failure | |
| DGF | 1.62 (1.43–1.82, <0.001) | 2.63 (2.20–3.15, <0.001) | 1.62 (1.44–1.82, <0.001) |
| Previous liver transplant | 1.47 (1.29–1.68, <0.001) | 1.27 (1.01–1.60, 0.04) | 1.47 (1.29–1.67, <0.001) |
| Recipient HCV | 1.45 (1.32–1.61, <0.001) | 1.49 (1.26–1.76, <0.001) | 1.42 (1.29–1.57, <0.001) |
| Previous kidney transplant | 1.38 (1.13–1.69, <0.001) | 1.46 (1.07–1.98, 0.02) | 1.34 (1.10–1.62, 0.004) |
| Hospitalized pretransplant | 1.32 (1.18–1.49, <0.001) | 1.18 (0.96–1.43, 0.1) | 1.33 (1.19–1.49, <0.001) |
| DCD | 1.31 (1.01–1.71, 0.04) | 1.49 (0.98–2.25, 0.1) | 1.40 (1.08–1.80, 0.01) |
| Donor age, per 10 years | 1.17 (1.13–1.22, <0.001) | 1.31 (1.23–1.39, <0.001) | 1.17 (1.13–1.22, <0.001) |
| Recipient age, per 10 years | 1.15 (1.09–1.21, <0.001) | 0.93 (0.85–1.01, 0.1) | 1.12 (1.06–1.18, <0.001) |
| Transplant year | 0.95 (0.93–0.96, <0.001) | 0.95 (0.92–0.97, <0.001) | 0.94 (0.93–0.96, <0.001) |
| Pretransplant dialysis | 1.08 (0.97–1.21, 0.2) | 1.25 (1.03–1.51, 0.02) | 1.06 (0.96–1.19, 0.3) |
| Donor creatinine, per mg/dL | 1.04 (0.99–1.09, 0.2) | 1.10 (1.04–1.16, 0.001) | 1.03 (0.98–1.09, 0.3) |
| Donor female | 1.01 (0.91–1.12, 0.9) | 1.07 (0.91–1.27, 0.4) | 1.02 (0.92–1.13, 0.7) |
| Use of induction immunosuppression | 1.01 (0.90–1.15, 0.8) | 0.94 (0.77–1.15, 0.6) | 1.01 (0.90–1.14, 0.8) |
| Donor cold ischemia time, liver, hours | 1.001 (0.99–1.09, 0.2) | 1.01 (0.99–1.03, 0.3) | 1.01 (0.99–1.02, 0.5) |
| MELD | 0.99 (0.99–1.002, 0.1) | 1.00 (0.97–1.00, 0.05) | 0.99 (0.98–1.001, 0.1) |
| Donor BMI, per 5 kg/m2 | 0.96 (0.92–1.01, 0.1) | 0.97 (0.90–1.04, 0.4) | 0.96 (0.92–1.001, 0.1) |
| Recipient female | 0.96 (0.86–1.07, 0.4) | 1.03 (0.87–1.23, 0.7) | 0.94 (0.85–1.05, 0.3) |
| Donor share type – Local | Reference | Reference | Reference |
| Regional | 0.95 (0.81–1.10, 0.5) | 1.22 (0.98–1.53, 0.1) | 0.90 (0.78–1.05, 0.2) |
| National | 1.12 (0.80–1.58, 0.5) | 1.15 (0.68–1.95, 0.6) | 1.05 (0.74–1.48, 0.8) |
| Recipient race – white | Reference | Reference | Reference |
| Black | 1.14 (0.995–1.30, 0.1) | 1.36 (1.11–1.67, 0.004) | 1.12 (0.98–1.27, 0.1) |
| Other | 0.85 (0.67–1.08, 0.2) | 0.94 (0.74–1.19, 0.6) | 0.87 (0.69–1.10, 0.3) |
| Donor race – White | Reference | Reference | Reference |
| Black | 1.04 (0.91–1.19, 0.6) | 1.24 (1.003–1.54, 0.05) | 1.09 (0.96–1.25, 0.2) |
| Other | 1.02 (0.78–1.34, 0.9) | 1.17 (0.76–1.79, 0.5) | 1.00 (0.76–1.31, 1.0) |