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. Author manuscript; available in PMC: 2020 Jul 13.
Published in final edited form as: Nat Neurosci. 2020 Jan 13;23(2):217–228. doi: 10.1038/s41593-019-0572-3

Extended Data Fig. 6. Fiber photometry imaging of GCaMP6s fluorescence from the terminals of PVT neurons in the IL.

Extended Data Fig. 6

a. Schematic of the viral vector strategy and optical fiber placement used for fiber photometry imaging of GCaMP6s fluorescence from the IL terminals of Type II PVT neurons. b. Left: average GCaMP6s response to footshocks from IL terminals of Type II PVT neurons. Footshock duration depicted by the red line above the trace, n = 6 mice. Right: quantification of GCaMP6s responses to footshocks. AUC, Before, −0.0015 ± 0.00076; After, −5.82 ± 0.39, n = 6 mice, **P=0.0.00003, two-sided Paired sample t-test. c. Left: average GCaMP6s response to social interaction from the IL terminals of Type II PVT neurons. The duration of the interaction bouts is depicted by the red line above the trace, n = 6 mice. Right: quantification of GCaMP6s responses to social interaction. AUC, Before, −0.00072 ± 0.008; After, −36.33 ± 10.48, n = 6 mice, **P=0.0.00003, two-sided Paired sample t-test. Box chart legend: box is defined by 25th, 75th percentiles, whiskers are determined by 5th and 95th percentiles, and mean is depicted by the square symbol. Data shown as mean ± s.e.m.