Skip to main content
. Author manuscript; available in PMC: 2020 Jul 22.
Published in final edited form as: Nature. 2020 Jan 22;578(7793):172–176. doi: 10.1038/s41586-019-1928-2

Extended Data Figure 6 ∣. Solution characterization of self-assembled BMC3 and BMC4 cages.

Extended Data Figure 6 ∣

The oligomerization state of BMC3 cages as monitored by AUC measurements following: a, incubation with various first-row transition metal ions b, incubation with Zn2+ and Fe3+ (Fe(acetylacetonate)3) and c, Disassembly via sequestration of metal ions by EDTA. d, AUC profiles of BMC variants after equilibration for two hours at the indicated temperatures (top). Thermal unfolding of BMC variants as measured by circular dichroism spectroscopy at 222 nm (bottom). e, Treatment with chemical reductants of different reduction potentials. ns-TEM micrographs are shown for cage samples incubated with chemical reductants.