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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Cancer Prev Res (Phila). 2019 Sep 25;13(2):153–162. doi: 10.1158/1940-6207.CAPR-19-0356

FIGURE 1.

FIGURE 1

Concentration of metabolites of volatile organic compounds at baseline before study products were assigned, during Days 1 and 2 of each arm, and during abstention from nicotine and tobacco products. Square brackets = significant difference between combustible cigarettes (CC) and e-cigarettes (EC); a = significantly lower than combustible cigarette use on Day 2; b = significantly lower than e-cigarette use on Day 2; c = significantly higher than e-cigarette use on Day 2. 2-HPMA = 2-hydroxypropylmercapturic acid; 3-HPMA = 3-hydroxypropylmercapturic acid; AAMA = 2-carbamoylethylmercapturic acid; CNEMA = 2-cyanoethylmercapturic acid; HEMA = 2-hydroxyethylmercapturic acid (acrylonitrile, vinyl chloride, ethylene oxide); HPMMA = 3-hydroxy-1-methyl-propylmercapturic acid; MHBMA-1+2 = sum of isomers 1-hydroxy-3-buten-2-yl-mercapturic acid and 2-hydroxy-3-buten-1-yl-mercapturic acid; MHBMA-3 = 4-hydroxy-2-buten-1-yl-mercapturic acid; MMA = methylmercapturic acid; and, PMA = phenylmercapturic acid.