Table 1.
Demographics of Participants with and without Hypoglycemia during MMTT
| Hypoglycemia [−] | Hypoglycemia [+] | p-value | |||
|---|---|---|---|---|---|
| NGT (n=11) | AGT (n=14) | Total (n=25) | (n=9) | ||
| Female, n (%) | 5 (45) | 6 (43) | 11 (44) | 6 (67) | 0.24 |
| Age | 21.5 (16–50) | 25.6 (18–42) | 23.8 (16–50) | 27.3 (16–44) | 0.34 |
| HbA1c, % | 5.5 (4.7–6.2) | 5.4 (4.8–6.4) | 5.4 (4.7–6.4) | 5.6 (5.3–6.3) | 0.11 |
| Fasting Glucose, mg/dL | 79 (64–90) | 91 (73–104) | 85 (64–104) | 82 (77–93) | 0.27 |
| OGTT 1-hour Glucose, mg/dL | 126 (96–154) | 189 (129–253) | 161 (96–253) | 181 (121–260) | 0.23 |
| OGTT 2-hour Glucose, mg/dL | 88 (66–116) | 118 (34–178) | 105 (34–178) | 132 (87–196) | 0.18 |
| Height-z | −0.25 (− 1.3 – 1.1) | −0.35 (− 2.6 – 1.9) | −0.3 (− 2.6 – 1.9) | −0.3 (− 1.3 – 1.2) | 0.98 |
| BMI-z | 0.3 (−1.2 – 1.8) | −0.05 (−2.3–1.8) | 0.1 (−2.3 – 1.8) | 0.34 (−0.2 – 0.7) | 0.55 |
| FEV1-% Predicted | 87 (58–113) | 77 (51–112) | 81.7 (51–113) (n=24) | 79.3 (54–104) | 0.61 |
| Genotype, n (%) with 1 delF508 | 8 (73) | 13 (93) | 21 (84) | 9 (100) | 0.21 |
| Genotype, n (%) with 2 delF508 | 3 (27) | 10 (71) | 13 (52) | 4 (44) | 0.71 |
Continuous data expressed as mean (min-max). Of note, 1 subject is missing pulmonary function testing. Statistical analyses were performed between the Hypoglycemia [−] and Hypoglycemia [+] groups with p-values reported. No group differences were detected. FEV1= forced expiratory volume in 1 second.