Table 3. Univariate and multivariate analyses on the overall survival of 102 cases of ovarian cancer.
Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|
HR | P > |z| | 95% CI | HR | P > |z| | 95% CI | |
SPAG5 expression | ||||||
High versus low | 4.61 | 0.001* | 2.511–8.454 | 3.05 | 0.001* | 1.547–6.031 |
Age (years) | ||||||
≥60 versus <60 | 1.26 | 0.412 | 0.723–2.204 | |||
Tumour size (cm) | ||||||
>5 versus ≤5 | 2.30 | 0.055 | 0.984–5.372 | |||
Histological type | ||||||
Serous versus mucinous versus Endometroid versus clear cell |
1.28 | 0.140 | 0.921–1.784 | |||
Pathological grade | ||||||
Grade 1 and 2 versus Grade 3 | 0.62 | 0.022* | 0.408–0.933 | 0.94 | 0.785 | 0.622–1.431 |
Lymph node metastasis | ||||||
Positive versus negative | 3.62 | 0.001* | 2.150–6.110 | 1.05 | 0.877 | 0.549–2.022 |
Distant metastasis | ||||||
Positive versus negative | 4.56 | 0.001* | 2.604–7.987 | 3.37 | 0.138 | 0.677–16.761 |
TNM stage | ||||||
Stage I versus Stage II versus Stage III versus Stage Stage IV |
0.25 | 0.001* | 0.163–0.392 | 0.13 | 0.005* | 0.031–0.543 |
P < 0.05