Table 3.
Univariate Cox’s proportional hazard model regression analyses of candidate microRNAs affecting MACCE-free survival
| Items | Univariate Cox’s regression | |
|---|---|---|
| P value | HR (95% CI) | |
| MiR-18a-5p (high vs. low) | 0.404 | 1.393 (0.640–3.032) |
| MiR-18b-5p (high vs. low) | 0.675 | 0.848 (0.392–1.833) |
| MiR-26b-5p (high vs. low) | 0.383 | 0.707 (0.325–1.540) |
| MiR-27a-3p (high vs. low) | 0.408 | 1.389 (0.638–3.025) |
| MiR-30e-5p (high vs. low) | 0.042 | 0.421 (0.183–0.968) |
| MiR-92a-3p (high vs. low) | 0.006 | 0.277 (0.111–0.690) |
| MiR-106a-5p (high vs. low) | 0.042 | 0.421 (0.183–0.969) |
| MiR-126-5p (high vs. low) | 0.007 | 0.284 (0.114–0.707) |
| MiR-134-5p (high vs. low) | 0.219 | 1.642 (0.745–3.618) |
| MiR-199a-3p (high vs. low) | 0.723 | 1.150 (0.532–2.486) |
| MiR-223-3p (high vs. low) | 0.409 | 0.720 (0.331–1.569) |
| MiR-423-5p (high vs. low) | 0.006 | 3.625 (1.455–9.028) |
| MiR-652-3p (high vs. low) | 0.103 | 0.511 (0.228–1.146) |
HR hazard ratio, CI confidence interval
P value < 0.05 was considered significant. MACCE: major adverse cardiac and cerebral event; All microRNAs were divided by median values as high and low expressions