Fig. 8.

BMS-470539 attenuated neuroinflammation, promoted M2 microglia activation, and reduced neutrophil infiltration at 24 h after SAH. Representative images of immunofluorescence staining and quantification of (A, B) IL-1β + cells; (C, D) Iba-1 activation; (E, F) MPO + cells; (G, H) CD206 + cells. N = 3 for each group. Scale bar=50μm. Data are shown as mean ± SD and compared by one-way ANOVA followed by the Tukey post hoc test. *p<0.05 versus sham, #p<0.05 versus SAH + vehicle, &p<0.05 versus SAH + BMS-470539.