Fig. 5.

Dynamic remodeling of proteome solubility involving a core enrichment of proteins involved in nucleocytoplasmic transport and SGs. (A) Overall proteome solubility changes due to treatments. Comparison of the proportion of protein amount in the supernatant fraction out of the total lysate measured by bicinchoninic acid assay between the control and the treatment groups. Error bars represent SD. N = 3 or 4. (B) List of proteins found in common as shown. (C) Venn diagram presents the overlaps of more insoluble or soluble proteins across six stresses. The area enclosed by the thick black line represents the overlap regions with, at least, three stresses. Protein–protein interaction of common proteins that became more insoluble (red) and more soluble (blue) in, at least, three stresses are shown. Purple bold represents known SG proteins.