Table 1.
Animal characteristics
| Sham + control | Sham + empa | MI + vehicle | MI + empa | |
|---|---|---|---|---|
| Body weight (g) | 288 ± 4 | 267 ± 2* | 271 ± 3* | 257 ± 2*,† |
| Haemoglobin (g/L) | 131 ± 7 | 144 ± 3* | 143 ± 2* | 150 ± 3† |
| Plasma sodium (mmol/L) | 126 ± 2 | 128 ± 3 | 131 ± 1* | 133 ± 1† |
| HbA1c (%) | 4.8 ± 0.2 | 5.0 ± 0.1 | 4.7 ± 0.1 | 4.9 ± 0.1 |
| HW indexed to tibial length (mg/mm) | 18.1 ± 0.4 | 17.2 ± 0.3 | 18.9 ± 0.6 | 16.7 ± 0.3† |
| Lung weight indexed to tibial length (mg/mm) | 25 ± 1 | 25 ± 1 | 31 ± 3 | 24 ± 1† |
Data are expressed as mean ± SEM
N = 13–15 in sham Control and sham + Empagliflozin groups; N = 20 and 20 in MI Control and MI + Empagliflozin groups, respectively
Empa empagliflozin, LV weight/TL Left ventricular weight/tibial length, LW/TL lung weight/tibial length ratio
* p < 0.05 vs. sham control group
†p < 0.05 vs. MI control group