Table 2.

Echocardiographic parameters

	Sham + control	Sham + empa	MI + vehicle	MI + empa
Heart rate (bpm)	382 ± 6	343 ± 6	350 ± 7	336 ± 7
Cardiac output (ml/min)	77 ± 2	65 ± 1*	56 ± 3*,‡	50 ± 2*,‡
FS (%)	56 ± 1	55 ± 1	21 ± 1*	22 ± 2
LVIDd (mm)	6.8 ± 0.1	6.6 ± 0.1	8.6 ± 0.2*	8.2 ± 0.2*,†
LVIDs (mm)	3.0 ± 0.1	3.0 ± 0.1	6.9 ± 0.2*	6.5 ± 0.2

Data are expressed as mean ± SEM. N = 24 in sham + control and sham + empa groups; N = 23 and 25 in MI + vehicle and MI + Empa groups, respectively

Empa empagliflozin, HR heart rate, FS fractional shortening, LVIDd left ventricular internal diameter in diastole, LVIDs left ventricular internal diameter in systole

* p < 0.05 vs. sham control group

^†p < 0.05 vs. MI + vehicle group

^‡p < 0.05 vs. Sham + empa