Figure 3.

The different criteria needed to diagnose Gorham-Stout disease. These include the presence of angiomatous tissue, evidence of progressive bone resorption and an osteolytic radiographic pattern. Moreover, absence of cellular atypia, dystrophic calcification, and visceral involvement should be noted as well, and the observed lesion should be non-ulcerative and non-expansive. Finally, to confirm the diagnosis, one must eliminate any metabolic, hereditary, neoplastic, infectious, or immunologic factors