. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Lancet Neurol. 2019 Dec 3;19(2):145–156. doi: 10.1016/S1474-4422(19)30394-1
This is an Open Access article under the CC BY NC-ND 4.0 license. http://creativecommons.org/licenses/by-nc-nd/4.0/