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. 2020 Feb 4;15:779–793. doi: 10.2147/IJN.S229576

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© 2020 He et al.

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In vivo anticancer effects of PEG-PLA/P105/PTX micelles combined with Ax. (A) The changes in pulmonary tumor size detected at 0, 5, 10, 15 days by IVIS. The left-side mice in each group represent the bright-field picture. (B) LC3 proteins of the lung tissues measured by Western blotting and (C) quantitative analysis of LC3-II protein of the lung tissues. (D) Survival curves and (E) median survival times of the pulmonary tumor-bearing mice at different treatment groups. *P < 0.05, **P < 0.01, ***P < 0.001.

Notes: (C) Data are represented as mean ± SD, n=3; (D) and (E) Data are represented as mean ± SD, n = 10.

Abbreviations: PEG-PLA/P105/PTX, PEG-PLA/P105/PTX micelles; Ax, ambroxol; PTX, paclitaxel.