. 2020 Feb 4;15:779–793. doi: 10.2147/IJN.S229576

Table 1.

IC50 Values of PEG-PLA/P105/PTX micelles in Combination with 20, 50 and 100 μM of Ax on A549 Cells Following 24, 48 and 72 hrs Treatment, Respectively.

Incubation Time (h)	IC50 (ng/mL)
Incubation Time (h)	PEG-PLA/P105/PTX Micelles	PEG-PLA/P105/PTX Micelles + 20 μM Ax	PEG-PLA/P105/PTX Micelles + 50 μM Ax	PEG-PLA/P105/PTX Micelles + 100 μM Ax
24	87.09 ± 4.12	34.45 ± 1.78^&&&	7.80 ± 0.97^###	1.14 ± 0.08***
48	41.53 ± 2.69	18.22 ± 1.32^&&&	2.45 ± 0.17^###	0.48 ± 0.06***
72	10.73 ± 0.61	4.78 ± 0.39^&&&	0.96 ± 0.12^###	0.19 ± 0.03***

Notes: Data are represented as mean ± SD, n=6. ^&&&P<0.001 vs PTX, ^###P<0.001 vs PEG-PLA/P105/PTX micelles + 20 μM Ax, ***P<0.001 vs PEG-PLA/P105/PTX micelles + 50 μM Ax.

Abbreviations: Ax, ambroxol; PTX, paclitaxel.