Table 2.
Person-years | # of cases | Age-adjusted HR (95% CI) |
MV-adjusted HR-1 (95% CI)† |
MV-adjusted HR- 2 (95% CI)‡ |
MV-adjusted HR- 3 (95% CI)* |
|
---|---|---|---|---|---|---|
Psoriasis | ||||||
Q1 | 401,723 | 289 | 1 [reference] | 1 [reference] | 1 [reference] | -- |
Q2 | 403,689 | 282 | 0.97 (0.82, 1.14) | 0.96 (0.81, 1.13) | 0.96 (0.81, 1.13) | -- |
Q3 | 403,163 | 301 | 1.04 (0.88, 1.22) | 1.03 (0.87, 1.21) | 1.03 (0.87, 1.21) | -- |
Q4 | 403,457 | 250 | 0.88 (0.74, 1.04) | 0.89 (0.75, 1.06) | 0.90 (0.75, 1.06) | -- |
Q5 | 402,473 | 310 | 1.09 (0.93, 1.28) | 1.15 (0.98, 1.36) | 1.16 (0.99, 1.37) | -- |
P for trend | 0.43 | 0.11 | 0.09 | -- | ||
Psoriatic Arthritis | ||||||
Q1 | 404,950 | 62 | 1 [reference] | 1 [reference] | 1 [reference] | -- |
Q2 | 406,978 | 50 | 0.81 (0.55, 1.17) | 0.82 (0.56, 1.19) | 0.82 (0.56, 1.19) | -- |
Q3 | 406,043 | 48 | 0.77 (0.53, 1.13) | 0.82 (0.56-1.20) | 0.83 (0.56, 1.21) | -- |
Q4 | 406,618 | 45 | 0.75 (0.51, 1.11) | 0.83 (0.56-1.22) | 0.83 (0.57-1.23) | -- |
Q5 | 405,664 | 57 | 0.94 (0.66, 1.35) | 1.12 (0.78-1.62) | 1.14 (0.79, 1.65) | -- |
P for trend | 0.89 | 0.39 | 0.36 | -- | ||
Atopic dermatitis | ||||||
Q1 | 226,110 | 83 | 1 [reference] | 1 [reference] | 1 [reference] | 1 [reference] |
Q2 | 226,423 | 86 | 1.03 (0.76, 1.39) | 1.04 (0.77, 1.41) | 1.04 (0.77 1.41) | 1.05 (0.78, 1.42) |
Q3 | 226,519 | 75 | 0.89 (0.65, 1.22) | 0.91 (0.66, 1.24) | 0.91 (0.66, 1.25) | 0.92 (0.67, 1.25) |
Q4 | 226,054 | 86 | 1.03 (0.76, 1.39) | 1.06 (0.78, 1.44) | 1.06 (0.78, 1.44) | 1.07 (0.79, 1.45) |
Q5 | 225,704 | 73 | 0.87 (0.64, 1.19) | 0.91 (0.66, 1.25) | 0.91 (0.66, 1.26) | 0.92 (0.67, 1.27) |
P for trend | 0.36 | 0.54 | 0.55 | 0.58 |
HR, Hazard ratio; MV, multivariable
Adjusted for age, race, BMI, smoking, alcohol intake, calorie consumption, exercise (METs)
Adjusted for age, race, BMI, smoking, alcohol intake, calorie consumption, exercise (METs), cardiovascular disease, hypertension, hypercholesterolemia, diabetes
Adjusted for age, race, BMI, smoking, alcohol intake, calorie consumption, exercise (METs), cardiovascular disease, hypertension, hypercholesterolemia, diabetes, asthma