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. Author manuscript; available in PMC: 2021 Feb 6.
Published in final edited form as: Mol Cell. 2019 Dec 31;77(3):556–570.e6. doi: 10.1016/j.molcel.2019.11.012

Figure 1. Su(var)2–10 depletion in the Drosophila female germline leads to embryo ventralization.

Figure 1.

(A) Su(var)2–10 GLKD using two different shRNAs (shSv210–1 and shSv210–2) leads to reduced transcript level. Plot shows the relative expression of Su(var)2–10 in control and Su(var)2–10 depleted ovaries (RT-qPCR). Dots correspond to three independent biological replicates; bars indicate the mean and SD.

(B) Su(var)2–10 protein level is reduced upon GLKD. Western blot shows the levels of MT-Gal4 driven GFP-Su(var)2–10 in ovaries of control (shW) and Su(var)2–10 GLKD flies. Tubulin (Tub) is used as loading control.

(C) Su(var)2–10 GLKD causes egg shell ventralization. Table shows the proportion of eggs from control (shW) and Su(var)2–10 GLKD ovaries displaying each class of ventralization phenotype ordered by severity (Images adopted from (Meignin and Davis, 2008)).