Table 1.
Tumor | Tumorigenicity | Invasiveness | Clinical Stage* | KRAS status† | Codon mutation details‡ | ||
---|---|---|---|---|---|---|---|
Time to growtha | Metastatic rateb | G12 | G12 | G12 | |||
T608 | 2.0 months | 100% | met | mut | aa12(G➔D) | None | None |
T366 | 2.8 months | 75% | met | mut | aa12(G➔D) | None | None |
T395 | 4.5 months | 40% | pri | mut | aa12(G➔L) | NT | NT |
T449 | 2.0 months | 0% | pri | mut | aa12(G➔D) | NT | NT |
T188 | 6.0 months | 100% | pri | wt | None | NT | NT |
T738 | 7.2 months | 25% | pri | wt | None | None | None |
- in mouse model
– in abdominal or liver
met - metastatic; pri – primary
mut - mutant; wt - wild-type.
NT - not tested.