Table 2.

Brain regions significantly activated during the PVSAT for the different groups and sessions (height threshold of p < 0.05 FWE-corrected, extent threshold of 30 voxels)

Group	Cluster size	Voxel T	Voxel Z	MNI Coordinate: x y z (mm)	Laterality	Anatomical Location	Brodmann’s Area
HS	577	13.02	6.31	12 20 52	Right	Cingulate Gyrus	32
		11.64	6.03	−12 26 32	Left	Cingulate Gyrus	32
		9.55	5.54	−14 10 42	Left	Cingulate Gyrus	32
	199	10.33	5.74	−30 -48 54	Left	Precuneus	7
		8.19	5.15	−46 − 48 56	Left	Inferior Parietal Lobule	40
		7.58	4.95	-48 -48 48	Left	Inferior Parietal Lobule	40
	285	10.1	5.68	−42 -4 38	Left	Precentral Gyrus	6
		8.94	5.37	−32 0 42	Left	Middle Frontal Gyrus	6
		8.74	5.31	−42 -8 46	Left	Precentral Gyrus	6
	198	9	5.39	0–68 − 24	Right	Cerebellum
		8.22	5.16	14–58 -28	Right	Cerebellum
		8.05	5.1	0–52 -26	Right	Cerebellum
	113	8.52	5.25	-24 6 4	Left	Putamen
		7.92	5.06	−30 16 6	Left	Claustrum
PwMS (PRE)	3818	15.02	6.65	−26 0 58	Left	Sub-Gyral	6
		14.08	6.49	−6 10 48	Left	Medial Frontal Gyrus	32
		13.09	6.32	−48 8 22	Left	Inferior Frontal Gyrus	44
	1894	12.25	6.16	−30 -48 36	Left	Inferior Parietal Lobule	40
		11.77	6.06	−42 -50 48	Left	Inferior Parietal Lobule	40
		10.91	5.87	−14 -72 52	Left	Precuneus	7
	750	12	6.11	28–64 40	Right	Superior Parietal Lobule	7
		7.54	4.93	14–68 50	Right	Precuneus	7
	232	10.45	5.77	34–60 -36	Right	Cerebellum
	642	10.34	5.74	48–36 44	Right	Inferior Parietal Lobule	40
		10.09	5.68	36–36 32	Right	Postcentral Gyrus	2
		9.18	5.44	40–42 44	Right	Inferior Parietal Lobule	40
	188	9.4	5.5	34 22 0	Right	Insula	13
		9.34	5.48	32 22 8	Right	Insula	13
	48	8.91	5.36	−30 -78 26	Left	Superior Occipital Gyrus	39
	117	8.87	5.35	44 46 18	Right	Middle Frontal Gyrus	10
	51	7.7	4.99	−34 -60 -30	Left	Cerebellum
	32	7.33	4.86	10–72 -34	Right	Cerebellum
PwMS (POST)	752	11.44	5.99	−26 -64 40	Left	Superior Parietal Lobule	7
		10.69	5.82	−16 -62 46	Left	Precuneus	7
		9.51	5.53	−10 -66 50	Left	Precuneus	7
	65	9.92	5.64	26–64 -52	Right	Cerebellum
	42	9.61	5.55	−42 -10 36	Left	Precentral Gyrus	6
	63	9.41	5.5	34–58 -34	Right	Cerebellum
	186	8.53	5.25	−50 8 22	Left	Inferior Frontal Gyrus	44
		8.19	5.15	−40 4 26	Left	Inferior Frontal Gyrus	9
	33	8.35	5.2	42–38 32	Right	Inferior Parietal Lobule	40
	118	8.24	5.16	−6 8 52	Left	Medial Frontal Gyrus	32
		7.87	5.04	−2 6 62	Left	Superior Frontal Gyrus	6
	59	8.07	5.11	−48 22 26	Left	Middle Frontal Gyrus	46
		7.96	5.07	−46 36 24	Left	Middle Frontal Gyrus	46