Table 4.

Brain regions showing significantly different activation during the PVSAT between groups (height threshold of p < 0.001 uncorrected, extent threshold of 30 voxels)

Contrast	Cluster Size	Voxel T	Voxel Z	MNI Coordinate: x y z (mm)	Laterality	Anatomical Location	Brodmann’s Area
PwMS (PRE) - HS	423	5.70	4.74	−8 12 36	Left	Cingulate Gyrus	24
		3.97	3.57	−12 4 54	Left	Medial Frontal Gyrus	6
		3.65	3.33	−20 16 52	Left	Superior Frontal Gyrus	8
	696	5.69	4.73	−40 42 12	Left	Middle Frontal Gyrus	10
		5.02	4.31	−48 28 16	Left	Inferior Frontal Gyrus	46
		4.74	4.12	−44 20 18	Left	Inferior Frontal Gyrus	45
	871	5.52	4.63	−42 -52 50	Left	Inferior Parietal Lobule	40
		4.16	3.71	−60 -40 38	Left	Inferior Parietal Lobule	40
	532	5.46	4.60	−32 -2 40	Left	Precentral Gyrus	6
		4.76	4.14	−40 -6 40	Left	Precentral Gyrus	6
		4.20	3.74	−34 -2 24	Left	Insula	13
	143	4.79	4.16	30 24 4	Right	Insula	13
	275	4.52	3.97	−22 -76 44	Left	Superior Parietal Lobule	7
		4.04	3.63	−12 -76 50	Left	Precuneus	7
	326	4.40	3.88	56–28 34	Right	Inferior Parietal Lobule	40
		4.20	3.74	42–34 28	Right	Inferior Parietal Lobule	40
		3.59	3.28	64–26 38	Right	Postcentral Gyrus	2
	67	4.38	3.87	28–68 44	Right	Superior Parietal Lobule	7
	43	4.29	3.81	−28 16 2	Left	Claustrum
	38	4.01	3.60	36 6 22	Right	Insula	13
	72	3.91	3.53	−10 -60 38	Left	Precuneus	7
		3.65	3.33	−4 -68 36	Left	Precuneus	7
HS - PwMS (PRE)	No suprathreshold clusters
PwMS (POST) - HS	122	4.48	3.94	−36 42 12	Left	Middle Frontal Gyrus	10
		4.01	3.6	−44 38 14	Left	Inferior Frontal Gyrus	46
	37	4.13	3.69	−12 14 32	Left	Cingulate Gyrus	24
	45	3.95	3.56	−8 -62 38	Left	Precuneus	7
	46	3.92	3.53	−32 -2 36	Left	Precentral Gyrus	6
HS - PwMS (POST)	60	4.02	3.61	40–24 6	Right	Superior Temporal Gyrus	13