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. 2020 Jan 22;98(2):161–177. doi: 10.1007/s00109-020-01874-2

Fig. 1.

Fig. 1

Lung cancer intratumoral heterogeneity at morphological and molecular levels. a Paraffin section of a lung tumor biopsy showing three main morphological subtypes within the same tumor. b Molecular and biomarker analysis confirming heterogeneity in EGFR mutation and in the c transcriptional signature of these three subtypes