Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Predicted 3D ligand binding pose of compound 7a (purple) in the HDAC1 (A) and HDAC2 (B) active sites overlapped with the binding pose of a known HDAC inhibitor from crystal structure 6G3O (green). The interacting residues are shown in line view, Zn ion is shown as a sky blue sphere. Dotted lines are used to visualize the protein–ligand interactions. Image prepared in Discovery Studio Visualizer.
