TABLE 3.

Diagnostic performance of various high-resolution computed tomography-derived measures for pulmonary hypertension defined as mean pulmonary artery (PA) pressure ≥25 mmHg on right heart catheterisation for subgroups with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)

	Subjects n	Sensitivity %	Specificity %	PPV	NPV
COPD
Inspiration
MPAD ≥29 mm	136	88.17	41.86	0.77	0.62
PA:Ao ≥1.0	136	50.54	88.37	0.90	0.45
MPAD and PA:Ao	136	50.54	88.37	0.90	0.45
MPAD or PA:Ao	136	88.17	41.86	0.77	0.62
Expiration
MPAD ≥29 mm	131	90.11	37.50	0.77	0.63
PA:Ao ≥1.0	131	50.55	85.00	0.88	0.43
MPAD and PA:Ao	131	49.45	85.00	0.88	0.43
MPAD or PA:Ao	131	91.21	37.50	0.77	0.65
ILD
Inspiration
MPAD ≥29 mm	235	91.24	37.76	0.67	0.76
PA:Ao ≥1.0	235	52.55	80.61	0.79	0.55
MPAD and PA:Ao	235	50.36	84.69	0.82	0.55
MPAD or PA:Ao	235	93.43	33.67	0.66	0.79
Expiration
MPAD ≥29 mm	231	91.97	32.98	0.67	0.74
PA:Ao ≥1.0	231	45.99	78.72	0.76	0.50
MPAD and PA:Ao	231	45.99	79.79	0.77	0.50
MPAD or PA:Ao	231	91.97	31.91	0.66	0.73

PPV: positive predictive value; NPV: negative predictive value; MPAD: main PA diameter; PA:Ao: PA to ascending aorta ratio.