Table 2.

Statistical correlation of heart pathology with brain pathology and UPDRS score

Correlation	Correlation coefficient	P-value
a-syn heart versus a-syn sum brain	0.588	<0.0001
a-syn heart versus a-syn medulla	0.694	<0.000001
a-syn heart versus a-syn amygdala	0.420	<0.000001
a-syn heart versus TH heart	−0.201	<0.05
a-syn sum brain versus TH heart	−0.279	<0.01
a-syn medulla versus TH heart	−0.0323	<0.001
a-syn amygdala versus TH heart	−0.155	NS
a-syn heart versus NF heart	−0.331	<0.0001
a-syn sum brain versus NF heart	−0.547	<0.0001
a-syn sum medulla versus NF heart	−0.612	<0.000001
a-syn sum amygdala versus NF heart	−0.445	<0.000001
UPDRS versus a-syn heart	0.284	<0.001
UPDRS versus TH heart	−0.178	0.08
UPDRS versus NF heart	−0.430	<0.0001

a-syn = pathologic alpha-synuclein; NF = neurofilament; sum = summation; TH = tyrosine hydroxylase; UPDRS = Unified Parkinson’s Disease Rating Scale.