Figure 5.
GLTs protect the hippocampal neurons from Aβ25-35 damage by inhibiting the ROCK signaling pathway. The ROCK signaling pathway inhibitor Y-27632 was added in the process of experiment. (a) The expression of apoptosis-related protein Bax, Bcl2, and caspase 3/cleaved caspase 3 in each group was detected by western blot. (b) The protein expression of ROCK signaling pathway-associated proteins ROCK1 and ROCK2 in each group was determined. N = 3; ∗P < 0.05 compared to the control group, #P < 0.05 compared to Aβ25-35 group.