Table 5.
Univariate and multivariate Cox regression analysis for overall graft loss and ABMR-related graft loss after the first year of transplantation.
| Graft loss after first year (184 events) | ABMR-related graft loss (52 events) | |||||
|---|---|---|---|---|---|---|
| Univariate analysis for graft loss | p value | Hazard ratio | 95% CI | p value | Hazard ratio | 95% CI |
| Male sex recipient | 0.99 | 1.00 | 0.75–1.34 | 0.81 | 1.06 | 0.62–1.84 |
| Age recipient (per year) | 0.009 | 0.98 | 0.98–0.99 | 0.052 | 0.98 | 0.91–1.00 |
| Age donor (per year) | 0.013 | 1.01 | 1.00–1.03 | 0.13 | 1.02 | 0.99–1.036 |
| Deceased donor kidney | 0.014 | 1.43 | 1.07–1.92 | 0.37 | 1.28 | 0.74–2.20 |
| Previous transplant | 0.010 | 1.56 | 1.11–2.19 | 0.024 | 1.99 | 1.09–3.63 |
| Number of HLA mismatches | 0.94 | 1.00 | 0.91–1.10 | 0.23 | 0.89 | 0.75–1.70 |
| PRA current pos | 0.096 | 1.30 | 0.95–1.77 | 0.14 | 1.52 | 0.86–2.67 |
| PRA peak serum pos | 0.54 | 0.90 | 0.65–1.25 | 0.50 | 1.25 | 0.64–2.44 |
| DSA present | 0.024 | 1.45 | 1.05–2.01 | 0.011 | 2.09 | 1.18–3.71 |
| DSA∗ deceased donor kidney | <0.001 | 2.12 | 1.46–3.07 | <0.001 | 3.39 | 1.83–6.25 |
|
| ||||||
| Multivariate analysis for graft loss | ||||||
| Age donor (per year) | 0.001 | 1.02 | 1.01–1.03 | — | — | — |
| Age recipient (per year) | 0.001 | 0.98 | 0.97–0.99 | 0.051 | 0.98 | 0.96–1.00 |
| DSA∗ deceased donor kidney | 0.035 | 2.14 | 1.06–4.35 | 0.017 | 4.94 | 1.32–18.43 |
∗Interaction term for variables.