Table 3.
Determinants of a short bleeding time (BT, the lower quartile) in coronary artery disease (CAD) patients and controls.
| Variable | CAD patients (BT < 202 sec) | Controls (BT < 324 sec) | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
| Age (y) | 1.02 (0.97-1.08) | 0.41 | 1.01 (0.95-1.08) | 0.69 | 1.20 (1.12-1.28) | <0.001 | 1.10 (1.00-1.21) | 0.06 |
| Current smoking | 1.34 (0.63-2.86) | 0.45 | 1.50 (0.57-3.99) | 0.42 | 0.53 (0.23-1.22) | 0.13 | 0.54 (0.18-1.62) | 0.27 |
| Diabetes | 0.77 (0.27-2.24) | 0.64 | 1.24 (0.31-4.87) | 0.76 | — | — | ||
| Anemia | 1.41 (0.53-3.74) | 0.49 | 1.11 (0.30-4.07) | 0.87 | 1.45 (0.47-4.46) | 0.52 | 1.61 (0.37-7.10) | 0.53 |
| ASA treatment | 0.62 (0.26-1.48) | 0.28 | 0.42 (0.12-1.44) | 0.17 | — | — | ||
| Statin treatment | 2.24 (1.01-4.97) | 0.048 | 4.34 (1.44-12.97) | 0.01 | — | — | ||
| Platelet count in the lower quartile (≤205 and ≤205 × 103/μL)∗ | 0.18 (0.05-0.63) | 0.007 | 0.22 (0.05-0.92) | 0.038 | 0.37 (0.13-1.02) | 0.05 | 0.36 (0.10-1.32) | 0.12 |
| FVIII > 150% | 1.11 (0.53-2.32) | 0.79 | 0.65 (0.23-1.83) | 0.41 | 1.96 (0.90-4.24) | 0.09 | 0.66 (0.21-2.05) | 0.48 |
| CLT in the lower quartile (≤74 and <68 min)∗ | 0.73 (0.30-1.77) | 0.49 | 1.02 (0.33-3.16) | 0.97 | 0.93 (0.39-2.20) | 0.87 | 2.53 (0.77-8.33) | 0.13 |
| K s in the lower quartile (<6.1 and ≤8 × 10−9 cm2)∗ | 4.32 (1.94-9.60) | <0.001 | 3.35 (1.15-9.73) | 0.027 | 21.27 (8.47-53.44) | <0.001 | 10.02 (2.45-40.97) | 0.001 |
| HRG in the lower quartile (≤28 and ≤56.9 μg/mL)∗ | 9.23 (4.04-21.07) | <0.001 | 9.19 (3.50-24.29) | <0.001 | 3.11 (1.40-6.87) | 0.005 | 1.11 (0.36-3.41) | 0.85 |