Table 4.

Change scores for the IPSS by PGI-I outcomes

PGI-I outcome	Moderate symptoms (n=88)			Severe symptoms (n=73)
	N (%)	Change	Missing	N (%)	Change
Very much better	3 (3.4)	6.5 (−50.7 to 63.7)	1	3 (4.1)	18 (1.7 to 34.3)
Much better	30 (34.1)	5.6 (3.7 to 7.5)	1	19 (26.0)	13.5 (10.5 to 16.5)
A little better	33 (37.5)	3.2 (1.7 to 4.8)	0	32 (43.8)	7.1 (5.3 to 9.0)
No change	19 (21.6)	1.3 (−1.7 to 4.3)	0	19 (26.0)	4.9 (2.3 to 7.6)
A little worse	3 (3.4)	−5.0 (−31.0 to 20.9)	0	0 (0.0)	–

These results are stratified by baseline symptom severity on the IPSS: moderate symptoms are scores of 8–19 and severe symptoms are scores of ≥20. Change in IPSSs were estimated by comparing symptom scores between baseline and 6 weeks. Mean change and 95% CIs are presented. Outcomes are inverted so that positive changes reflect symptom improvement. The PGI-I category ‘a little better’ reflects the MID for both questionnaires. None of the participants scored ‘much worsened’ or ‘very much worsened’ on the PGI-I.

IPSS, International Prostate Symptom Score; MID, minimal important difference; OAB-q SF, Overactive Bladder Questionnaire short form; PGI-I, Patient Global Impression of Improvement.