Table 1.
Baseline characteristics and demographics.
All patients (N = 123) | |
---|---|
Median age, years (range) | 43.0 (22.0–76.0) |
Female, n (%) | 62 (50.4) |
Median time since diagnosis, months (range)* | 51.7 (1.0–405.7) |
Mean mGH, μg/L (SD)† | 10.2 (22.2) |
Screening mGH stratum, n (%) | |
1.0–2.5 μg/L | 28 (22.8) |
>2.5 μg/L | 94 (76.4) |
Missing | 1 (0.8) |
Mean IGF-I, x ULN (SD)† | 2.7 (1.2) |
Diabetic status, n (%)‡ | |
Diabetic | 52 (42.3) |
Pre-diabetic | 60 (48.8) |
Non-diabetic | 11 (8.9) |
Treatment prior to enrollment, n (%) | |
Lanreotide 120 mg | 41 (33.3) |
Octreotide 30 mg | 29 (23.6) |
Octreotide 40 mg | 53 (43.1) |
Three patients were enrolled and received pasireotide, who had been treated with octreotide or lanreotide for <3 months, noted as protocol deviations;
One patient had missing mGH and IGF-I values at baseline;
Classification of patients as diabetic, pre-diabetic, or non-diabetic was performed according to multiple criteria as stated in the Methods. n, number of patients; SD, standard deviation.