Table 2.
Metformin (n = 52) | Placebo (n = 41) | p-value | |
---|---|---|---|
SES at follow-up | Mean (SD) | Mean (SD) | |
Education mothera | 3.0 (0.8) | 3.0 (0.9) | .910 |
n (%) | n (%) | ||
10 years primary school | 1 (2) | 0 | |
high school | 13 (28) | 13 (37) | |
less than 4 years of higher education | 19 (40) | 9 (26) | |
4 or more years of higher education | 14 (30) | 13 (37) | |
Mean (SD) | Mean (SD) | ||
Education fatherb | 2.7 (0.8) | 2.6 (0.8) | .673 |
n (%) | n (%) | ||
10 years primary school | 0 | 2 (6) | |
high school | 26 (54) | 15 (43) | |
3 years of higher education | 10 (21) | 12 (34) | |
5 or more years of higher education | 12 (25) | 6 (17) | |
Parents’ relation: | n (%) | n (%) | .614 |
Married | 27 (64) | 22 (69) | |
Cohabitant | 11 (26) | 6 (19) | |
Divorced/separated | 4 (10) | 3 (9) | |
Other | 0 | 1 (3) | |
Offspring characteristics at follow-up | Mean (SD) | Mean (SD) | |
Age (years) | 7.7 (2.7) | 7.7 (2.6) | .958 |
Weight (kg) | 34.3 (18.3) | 30.8 (11.1) | .324 |
Weight z-score | 0.60 (1.2) | 0.31 (1.2) | .280 |
Height (cm) | 131.7 (17.4) | 130.2 (14.1) | .672 |
Height z-score | 0.17 (0.9) | 0.02 (1.1) | .491 |
BMI | 18.7 (4.4) | 17.6 (2.9) | .235 |
Head circumference (cm) | 53.1 (2.2) | 53.0 (1.9) | .804 |
Head circumference z-score | 0.49 (1.5) | 0.37 (1.3) | .696 |
Tanner stagec | 1.5 (1.2) | 1.4 (0.8) | .471 |
SES socioeconomic status
a maternal education measured on a scale 1–4 (1:10 y primary school, 2: high school, 3: less than 4 years of higher education, 4: 4 or more years of higher education) b paternal education measured on a scale 1–4 (1: 10 y primary school, 2: high school, 3: 3 years of higher education, 4: 5 or more years of higher education) c: scale 1–5, 1 = prepubertal, 5 = adult size genitals and breast, adult pubic hair growth