Table 4.
Linear model of prediction of WPPSI-II/WISC-IV scores. Adjusted for parents’ educational level
| B (95% CI) | SE B | β | p-value | R2 | ||
|---|---|---|---|---|---|---|
| Full scale IQ | 0.10 | |||||
| Metformin/placebo | 1.6 (−3.6, 6.7) | 2.59 | 0.55 | .550 | ||
| Mother’s education | 4.6 (1.3, 8.0) | 1.68 | 0.32 | .007 | ||
| Father’s education | −0.5 (−3.8, 2.9) | 1.69 | −0.03 | .788 | ||
| Verbal comprehension | 0.09 | |||||
| Metformin/placebo | 2.2 (−4.4, 8.7) | 3.30 | 0.07 | .513 | ||
| Mother’s education | 5.4 (1.1, 9.6) | 2.14 | 0.30 | .014 | ||
| Father’s education | −0.4 (−4.7,3.8) | 2.15 | −0.03 | .836 | ||
| Working memory | 0.07 | |||||
| Metformin/placebo | 2.4 (−3.3, 8.2) | 2.89 | 0.09 | .404 | ||
| Mother’s education | 4.1 (0.4, 7.8) | 1.87 | 0.26 | .030 | ||
| Father’s education | −0.5 (−4.2, 3.3) | 1.88 | −0.03 | .802 | ||
| Perceptual organization | 0.10 | |||||
| Metformin/placebo | 1.5 (−4.9, 7.9) | 3.21 | 0.05 | .640 | ||
| Mother’s education | 5.5 (1.4, 9.6) | 2.08 | 0.31 | .010 | ||
| Father’s education | 0.3 (−3.8, 4.5) | 2.09 | 0.02 | .873 | ||
| Processing speed | 0.02 | |||||
| Metformin/placebo | −3.2 (−11.1, 4.7) | 3.97 | −0.09 | .419 | ||
| Mother’s education | 1.9 (−3.2, 7.0) | 2.57 | 0.09 | .469 | ||
| Father’s education | −2.7 (−7.8, 2.4) | 2.58 | −0.13 | .299 |
WPPSI-III Wechsler Preschool and Primary Scale of Intelligence - Third edition
WISC-IV Wechsler Intelligence Scale for Children - Fourth edition