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. Author manuscript; available in PMC: 2020 Feb 10.
Published in final edited form as: Eur J Neurol. 2017 Oct 4;24(12):1464–1470. doi: 10.1111/ene.13440

Table 4.

Galectin-3 and the hazard ratio of ischaemic stroke, stratified by median age

Model N Q1 Q2 Q3 Q4 P value overall
1. Age < 64
 A 489 Referent 2.1 (1.1, 4.0), P = 0.03 3.0 (1.6, 5.8), P < 0.001 2.0 (1.0, 4.2), P = 0.06 0.008
 B 489 Referent 2.7 (1.3, 5.4), P = 0.006 4.0 (1.9, 8.5), P < 0.001 2.4 (1.1, 5.3), P = 0.03 0.004
 C 443 Referent 1.6 (0.8, 3.5), P = 0.19 2.7 (1.1, 6.3), P = 0.02 1.6 (0.7, 4.0), P = 0.30 0.16
 D 443 Referent 1.6 (0.7, 3.5), P = 0.28 2.8 (1.1, 6.8), P = 0.03 1.7 (0.7, 4.6), P = 0.27 0.17
2. Age 64+
 A 984 Referent 1.0 (0.6, 1.6), P = 0.87 1.0 (0.6, 1.7), P = 0.91 1.3 (0.8, 2.1), P = 0.29 0.49
 B 984 Referent 0.8 (0.5, 1.3), P = 0.37 0.8 (0.5, 1.3), P = 0.37 1.0 (0.6, 1.5), P = 0.85 0.67
 C 919 Referent 0.7 (0.4, 1.2), P = 0.22 0.9 (0.5, 1.4), P = 0.55 0.9 (0.5, 1.4), P = 0.56 0.67
 D 919 Referent 0.7 (0.4, 1.2), P = 0.16 0.8 (0.5, 1.3), P = 0.38 0.8 (0.5, 1.4), P = 0.49 0.58

Models: A, unadjusted; B, adjusted for age, sex, race, age × race; C, model B + Framingham stroke risk factors (diabetes, systolic blood pressure, use of any antihypertensive medications, left ventricular hypertrophy, history of coronary artery disease, atrial fibrillation); D, model C + income, education. N, total number of participants in the analysis; Q, quartile.