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. Author manuscript; available in PMC: 2020 Feb 10.
Published in final edited form as: J Huntingtons Dis. 2019;8(2):221–232. doi: 10.3233/JHD-180341

Table 3.

Linear regression predicting health related quality of life outcomes

Functional Assessment
Coefficient SE ηp2 t-value (df) p-value
PROMIS
Depression
 Assessment (Change per year) −0.98 0.44 0.01 −2.25 (331) 0.0254
 FA 1.22 0.41 0.02 3.00 (534) 0.0029
 Positive Affect and Well-being −0.24 0.15 0.01 −1.65 (527) 0.1001
 Interaction (FA * PAW) −0.02 0.01 0.02 −2.99 (533) 0.0029
Anxiety
 Assessment (Change per year) −1.45 0.43 0.01 −3.41 (316) 0.0007
 FA 0.80 0.42 0.01 1.90 (551) 0.0579
 Positive Affect and Well-being −0.25 0.15 0.00 −1.68 (544) 0.0944
 Interaction (FA * PAW) −0.02 0.01 0.01 −1.99 (550) 0.0472
Anger
 Assessment (Change per year) 0.19 0.40 0.00 0.48 (442) 0.6324
 FA 1.09 0.47 0.01 2.34 (668) 0.0194
 Positive Affect and Well-being −0.15 0.17 0.00 −0.92 (665) 0.3571
 Interaction (FA * PAW) −0.02 0.01 0.01 −2.55 (666) 0.0109
Neuro-QoL
Satisfaction w/ Social Roles and Activities*
 Assessment (Change per year) 0.08 0.26 0.00 0.31 (440) 0.7570
 FA −0.25 0.30 0.00 −0.83 (648) 0.4064
 Positive Affect and Well-being 0.11 0.11 0.00 1.05 (643) 0.2947
 Interaction (FA * PAW) 0.01 0.01 0.01 2.22 (645) 0.0268
Ability to Participate in Social Roles and Activities*
 Assessment (Change per year) 0.11 0.31 0.00 0.35 (477) 0.7258
 FA −0.05 0.32 0.00 −0.16 (619) 0.8696
 Positive Affect and Well-being 0.13 0.11 0.00 1.16 (620) 0.2471
 Interaction (FA * PAW) 0.01 0.01 0.00 1.38 (616) 0.1687
Executive Function*
 Assessment (Change per year) 0.60 0.39 0.00 1.53 (327) 0.1260
 FA −0.05 0.38 0.00 −0.13 (546) 0.8977
 Positive Affect and Well-being −0.02 0.14 0.00 −0.14 (541) 0.8925
 Interaction (FA * PAW) 0.01 0.01 0.01 2.02 (546) 0.0440
Stigma
 Assessment (Change per year) −0.50 0.27 0.00 −1.85 (445) 0.0653
 FA −0.06 0.32 0.00 −0.20 (667) 0.8399
 Positive Affect and Well-being −0.30 0.11 0.01 −2.64 (665) 0.0086
 Interaction (FA * PAW) −0.004 0.01 0.00 −0.64 (666) 0.5201
Upper Extremities*
 Assessment (Change per year) −0.84 0.24 0.01 −3.53 (428) 0.0005
 FA −0.06 0.30 0.00 −0.21 (670) 0.8323
 Positive Affect and Well-being −0.26 0.11 0.01 −2.33 (701) 0.0201
 Interaction (FA * PAW) 0.02 0.01 0.02 3.05 (671) 0.0023
Lower Extremities*
 Assessment (Change per year) −0.35 0.25 0.00 −1.39 (438) 0.1646
 FA 0.12 0.31 0.00 0.38 (675) 0.7068
 Positive Affect and Well-being −0.10 0.11 0.01 −0.90 (677) 0.3694
 Interaction (FA * PAW) 0.01 0.01 0.01 2.06 (676) 0.0393
Emotional/Behavioral Dyscontrol
 Assessment (Change per year) −0.12 0.36 0.00 −0.35 (449) 0.7293
 FA 0.78 0.42 0.01 1.87 (663) 0.0623
 Positive Affect and Well-being −0.18 0.15 0.01 −1.22 (660) 0.2243
 Interaction (FA * PAW) −0.02 0.01 0.01 −2.21 (662) 0.0273
HDQLIFE
Chorea
 Assessment (Change per year) 0.19 0.21 0.00 0.91 (423) 0.3621
 FA −0.24 0.26 0.01 −0.90 (667) 0.3691
 Positive Affect and Well-being −0.04 0.09 0.01 −0.47 (672) 0.6406
 Interaction (FA * PAW) −0.004 0.005 0.00 −0.79 (668) 0.4288
Speech Difficulties
 Assessment (Change per year) −0.06 0.24 0.00 −0.25 (446) 0.8060
 FA −0.44 0.30 0.00 −1.50 (672) 0.1340
 Positive Affect and Well-being −0.07 0.11 0.00 −0.70 (674) 0.4811
 Interaction (FA * PAW) 0.001 0.01 0.00 0.05 (673) 0.9628
Swallowing Difficulties
 Assessment (Change per year) 0.53 0.24 0.00 2.21 (431) 0.0276
 FA −0.39 0.31 0.00 −1.28 (666) 0.2027
 Positive Affect and Well-being −0.06 0.11 0.00 −0.51 (670) 0.6087
 Interaction (FA * PAW) −0.001 0.01 0.00 −0.04 (667) 0.9707
Concern w/ Death and Dying
 Assessment (Change per year) 0.32 0.32 0.00 0.98 (449) 0.3257
 FA 1.05 0.38 0.02 2.78 (661) 0.0056
 Positive Affect and Well-being −0.17 0.13 0.00 −1.24 (654) 0.2145
 Interaction (FA * PAW) −0.02 0.01 0.02 −2.49 (658) 0.0129
Meaning and Purpose*
 Assessment (Change per year) −0.41 0.28 0.00 −1.43 (468) 0.1524
 FA −0.40 0.32 0.01 −1.25 (658) 0.2113
 Positive Affect and Well-being 0.47 0.12 0.02 4.05 (652) <.0001
 Interaction (FA * PAW) 0.01 0.01 0.01 1.69 (653) 0.0922

FA, Functional Assessment; PAW, Positive Affect and Well-Being; (df), degrees of freedom; all models control for gender and race.

*

Higher Scores indicate better outcomes.