Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2021 Feb 1.

Published in final edited form as: Cancer Causes Control. 2019 Dec 11;31(2):113–126. doi: 10.1007/s10552-019-01256-1

Table 4.

Mediation of Alcohol - Metabolite Associations by Dietary Fat and Carbohydrate Intakes

	Dietary Fat				Dietary Carbohydrate

	Proportion Mediated		ACME^a	Sensitivity	Proportion Mediated		ACME^a	Sensitivity

Metabolite	Proportion	95% CI^b	p-value	ρ^c	Proportion	95% CI^b	p-value	ρ^c
Lipids
myo-inositol	0.29	0.03 - 0.72	0.03	−0.2	0.33	0.06 - 0.79	0.02	−0.2
1-palmitoyl-2-oleoyl-GPC (16:0/18:1)	0.33	0.11 - 0.88	0.002	−0.2	0.29	0.02 - 0.87	0.04	−0.2
Cofactors and Vitamins
retinol	0.15	−0.08 - 0.50	0.19	−0.1	0.20	−0.04 - 0.61	0.09	−0.1

^a

ACME = average causal mediation effects

^b

CI = confidence interval

^c

ρ at ACME=0