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. 2019 May 22;17(5):e05676. doi: 10.2903/j.efsa.2019.5676

Table F.1.

Additional genotoxicity data (in vitro)

Chemical name [FL‐no] Test system in vitro Test object Concentrations of substance and test conditions Result Reference Comments
Allyl α‐ionone [07.061] Micronucleus induction Human peripheral blood lymphocytes 12.50, 20.00, 25.00 and 27.50 μg/mLa , b Negative Lloyd (2014) The MNBN cell frequencies in all treated cultures fell within the normal range. This study completes the study by Lloyd (2013a), (Table E.1) and complies with OECD Guideline 487
a

Without S9 metabolic activation.

b

3‐h treatment with 21‐h recovery.