Table 1.

Summary of the design of the efficacy studies performed in chickens for fattening

Study	Total no of animals Replicates per treatment (animals per replicate)	Composition basal diet (feed form)	Intended TYFER™ supplementation (mg/kg feed)	End points
				Zootechnical	Microbiological load in caecum
1a	480 8 (10)	Barley, wheat, soya (crumbs: starter; pellets: grower/finisher)	0 10 20 50 100 200	✓	✓
2b	576 12 (12)	Barley, wheat, soya (mash)	0 20 50 200	✓	No
3c	1,568 14 (14)	Wheat, barley, soybean meal (mash)	0 10 20 50 100 200 400 600	✓	No
4d	840 6 (35)	Wheat, barley, soybean meal (mash)	0 20 50 200	✓	✓
5e	800 10 (20)	Barley, wheat, soya (mash)	0 20 50 200	✓	✓
6f	1,120 8 (35)	Maize, soybean meal (mash)	0 20 50 200	✓	✓

^aTechnical dossier/Section IV/Annex IV.3.1.

^bTechnical dossier/Section IV/Annex IV.3.2.

^cTechnical dossier/Section IV/Annex IV.3.3.

^dTechnical dossier/Section IV/Annex IV.3.4.

^eTechnical dossier/Section IV/Annex IV.3.5.

^fTechnical dossier/Supplementary Information (November 2017)/Annex IV‐3‐8.