Table 3.
Type of data extracted and used for data presentation and synthesis
| Type of data extracted | |
|---|---|
| Identification number of the comparison | Endpoint (e.g. attained BMI, WAZ) |
| Bibliography | Allergy to (e.g. egg, fish, peanut), if relevant |
| Inclusion (or not) in main analysis | Age at outcome assessment |
| Inclusion (or not) in subgroup analysis | Point estimate |
| Tier | Lower bound of the confidence interval (as reported in the paper or calculated by EFSA) |
| Study design | Upper bound of the confidence interval (as reported in the paper or calculated by EFSA) |
| Study name | Unit/Type (e.g. OR, RR) |
| Country (abbreviation) | Adjusted (yes/no) |
| At‐risk group (yes/no) | Remarks |
| Heredity of allergy (yes/no, mixed population, unclear) | Statistical significance (significant/not significant) |
| Allergic symptoms at introduction of CFs (yes/no/unclear) | ‘Reverse causality addressed through’ (e.g. sensitivity analysis) |
| Characteristics of the population (e.g. children with heredity of T1DM) | ‘Earlier introduction associated with’ (in case of significant result) |
| Specific study group (e.g. breastfed, preterm) | Exposure assessment time point (e.g. multiple ≤ 6 months, as classified for appraisal, see Appendix B) |
| E1 (age of introduction of CFs when used as categorical variable, group 1) | Exposure assessment method (e.g. interview, questionnaire) |
| E2 (age of introduction of CFs when used as categorical variable, group 2) | Outcome assessment (e.g. parent's report of symptoms) |
| Age of introduction of CFs as a continuous variable (yes/no) | Reference data/cut‐offs/method used (e.g. BMI ≥ P99 of CDC 2000) |
| N1 (number of subjects, group 1) | Food (e.g. CFs in general, egg, fish, gluten) |
| N2 (number of subjects, group 2) | Specific food (e.g. egg yolk if ‘food’ is egg) |
| Total N (total number of subjects of the comparison) | Amount (when available) |
| Section in opinion | Comparator (in RCTs) |
| Outcome (e.g. BMI, weight) | List of confounders (included, considered, not considered) |
CDC 2000: growth charts by CDC released in 2000; BMI: body mass index; CDC: US Centers for Disease Control and Prevention; CF: complementary food; OR: odds ratio; RCT: randomised controlled trial; RR: risk ratio; T1DM: type 1 diabetes mellitus; WAZ: weight‐for‐age z‐score.