Table 9.

Panel of antimicrobial substances, ECOFFs, CBPs and concentration ranges (in mg/L) for Salmonella and E. coli (first panel)

Antimicrobial	Bacterial species	ECOFFa R: > (mg/L)	CBPa R: > (mg/L)	Current concentration range (mg/L) (No. of wells)	Suggested new concentration range (mg/L) (No. of wells)
Ampicillin	Salmonella	8	8	1–64 (7)	1–32 (6)
	E. coli	8	8
Cefotaxime	Salmonella	0.5	2	0.25–4 (5)	0.25–4 (5)
	E. coli	0.25	2
Ceftazidime	Salmonella	2	4	0.25–8 (6)	0.25–8 (6)
	E. coli	0.5	4
Meropenem	Salmonella	0.125	8	0.03–16 (10)	0.03–16 (10)
	E. coli	0.125	8
Nalidixic acid	Salmonella	16	NA	4–128 (6)	4–64 (5)
	E. coli	16	NA
Ciprofloxacin	Salmonella	0.06	0.06	0.015–8 (10)	0.015–8 (10)
	E. coli	0.06	0.5
Tetracycline	Salmonella	8	NA	2–64 (6)	2–32 (5)
	E. coli	8	NA
Colistin	Salmonella	2 (EFSA)	2	1–16 (5)	1–16 (5)
	E. coli	2	2
Gentamicin	Salmonella	2	4	0.5–32 (7)	0.5–16 (6)
	E. coli	2	4
Trimethoprim	Salmonella	2	4	0.25–32 (8)	0.25–16 (7)
	E. coli	2	4
Sulfamethoxazole	Salmonella	256 (EFSA)	NA	8–1024 (8)	8–512 (7)
	E. coli	64	NA
Chloramphenicol	Salmonella	16	8	8–128 (5)	8–64 (4)
	E. coli	16	8
Azithromycin	Salmonella	16 (EFSA)	NA	2–64 (6)	2–64 (6)
	E. coli	16 (EFSA)	NA
Tigecycline	Salmonella	1 (EFSA)	NA	0.25–8 (6)	0.25–8 (6)
	E. coli	1 (EFSA)	2
Amikacin	Salmonella	NA	16	–	4–256 (7)
	E. coli	8	16	–

NA: not available. ECOFF: epidemiological cut‐off value; CBP: clinical breakpoint;

^aEUCAST ECOFFs and CBPs as available on the EUCAST website, last accessed on 6.3.2019.