Table 10.
Panel of antimicrobial substances, EUCAST ECOFFs and concentration ranges used for testing Salmonella spp. and E. coli isolates, resistant to cefotaxime, ceftazidime or meropenem (second panel)
| Antimicrobial | Salmonella EUCAST ECOFFa | E. coli EUCAST ECOFFa | Concentration range, mg/L (no. of wells) |
|---|---|---|---|
| Cefoxitin | > 8 | > 8 | 0.5–64 (8) |
| Cefepime | NAb | > 0.125 | 0.06–32 (10) |
| Cefotaxime + clavulanic acid | NA | NA | 0.06–64 (11) |
| Ceftazidime + clavulanic acid | NA | NA | 0.125–128 (11) |
| Meropenem | > 0.125 | > 0.125 | 0.03–16 (10) |
| Temocillin | NAc | NAc | 0.5–64 (8) |
| Imipenem | > 1 | > 0.5 | 0.12–16 (8) |
| Ertapenem | NAd | NAd | 0.015–2 (8) |
| Cefotaxime | > 0.5 | > 0.25 | 0.25–64 (9) |
| Ceftazidime | > 2 | > 0.5 | 0.25–128 (10) |
ECOFFs: epidemiological cut‐off values; EUCAST: European Committee on Antimicrobial Susceptibility Testing (last accessed on 6.3.2019); NA: not available.
EUCAST epidemiological cut‐off values available as the Decision 2013/652/EU was drafted (2013). For some antimicrobials, these values have been updated. To allow comparison with the data collected in previous years, the ECOFFs laid down in the legislation have been considered.
For cefepime the cut‐off value used in the analysis for Salmonella spp. was > 0.125 mg/L.
For temocillin the cut‐off value used in the analysis was > 32 mg/L.
For ertapenem, the cuff‐off value used in the analysis was > 0.06 mg/L.