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. 2018 Oct 17;16(10):e05423. doi: 10.2903/j.efsa.2018.5423

Table D.6.

Ames test results for 2‐methylcrotonaldehyde [FL‐no: 05.095] and 2‐methylpent‐2‐enal [FL‐no: 05.090]

Register name [FL‐no] S9 Nakajima, 2006 Bowen (2011) Ballantyne (2011) Comment Conclusion
2‐Methylcrotonaldehyde [05.095] − Positive Indication for a weak mutagenic activity At least the indication is reproducible Indication for a mutagenic activity based on two studies
+ Positive Indication for a weak mutagenic activity At least the indication is reproducible Indication for a mutagenic activity based on two studies
2‐Methylpent‐2‐enal [05.090] − Negative Indication for a weak mutagenic activity The indication was not reproducible in different studies. Inconsistent results Indication for a weak mutagenic activity based on the results of one study and structural similarity with 2‐methylcrotonaldehyde [FL‐no: 05.095]
+ Negative Indication for a weak mutagenic activity The indication was not reproducible in different studies. Inconsistent results Indication for a weak mutagenic activity based on the results of one study and structural similarity with 2‐methylcrotonaldehyde [FL‐no: 05.095]