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. 2018 May 16;16(5):e05243. doi: 10.2903/j.efsa.2018.5243

Table 11.

Opium alkaloids ratios in poppy seed samples compared to morphine

Substance Origin N Ratio to morphinea
Min P25 Median P75 P95b Max
Codeine High‐morphine 142 < 0.01 0.04 0.14 0.29 1.08 713
Low‐morphine 1,086 0.01 0.10 0.14 0.20 0.51 0.97
Unknown 257 0.01 0.09 0.15 0.27 0.67 2.33
Total 1,485 < 0.01 0.10 0.14 0.21 0.75 713
Thebaine High‐morphine 123 0.01 0.11 0.29 14.0 135 227
Low‐morphine 936 < 0.01 0.08 0.14 0.22 0.48 1.86
Unknown 143 < 0.01 0.07 0.12 0.19 0.52 1.10
Total 1,202 < 0.01 0.08 0.14 0.24 0.84 227
Oripavine High‐morphine 46 < 0.01 0.01 0.87 4.34 n.a. 43.4
Low‐morphine 15 < 0.01 0.01 0.01 0.02 n.a. 0.47
Unknown 23 < 0.01 0.01 0.02 0.05 n.a. 0.21
Total 84 < 0.01 0.01 0.04 0.87 19.9 43.4
Noscapine High‐morphine 26 < 0.01 < 0.01 < 0.01 < 0.01 n.a. 0.75
Low‐morphine 939 < 0.01 0.04 0.07 0.14 0.62 6.75
Unknown 127 < 0.01 0.01 0.05 0.09 0.23 0.48
Total 1,092 < 0.01 0.03 0.07 0.13 0.57 6.75
Papaverine High‐morphine 26 < 0.01 < 0.01 < 0.01 < 0.01 n.a. 0.76
Low‐morphine 272 < 0.01 0.01 0.02 0.11 0.76 0.76
Unknown 87 < 0.01 < 0.01 0.01 0.05 n.a. 0.76
Total 385 < 0.01 0.01 0.02 0.09 0.76 0.76

N: number of samples; n.a.: not applicable; Max: maximum; Min: minimum; P: percentile.

a

Calculated by dividing the opium alkaloid upper bound concentration by the morphine upper bound concentration. Concentrations were expressed as mmol/kg.

b

The 95th percentile with less than 60 observations may not be statistically robust (EFSA, 2011b) and is therefore not calculated.