Figure 7.

A schematic and simplified diagram of some salient features of AHR signalling pathways

• Black solid arrows depict the canonical pathway, dashed arrows alternative pathways, and the red solid arrow an example of their intersection. The blue bar represents AHR, pink bar ARNT, green bar AIP, brown bars a dimer of HSP90, and the red dot p23 (Modified from Lindén et al., 2010).ER: oestrogen receptor; CaMK: Ca²⁺/calmodulin‐dependent kinase; Cox2: cyclooxygenase 2; APP: acute‐phase protein; DME: drug‐metabolising enzyme. See text for details