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. 2018 Aug 10;16(8):e05393. doi: 10.2903/j.efsa.2018.5393

Table B.1.

Overview of systematic reviews and meta‐analysis published since 2009 on the relationship between sugars and their sources and endpoints of interest

Reference Endpoint (population subgroup) Exposure
Anderson et al. ( 2009 ) Caries (adults and children) Sucrose including sucrose‐based carbonated soft drinks, baked goods, sweets and table sugar, as added to other foods and drinks
Auerbach et al. ( 2017 ) Obesity (children) Fruit juice
Avery et al. ( 2015 ) Obesity (children) SSBs
Bucher Della Torre et al. ( 2016 ) Obesity (children) SSBs
Chiavaroli et al. ( 2015 ) Blood lipids (adults and children) Fructose
Chiu et al. ( 2014 ) NAFLD (adults) Fructose
Chung et al. ( 2014 ) Liver health (adults) Fructose
Crowe‐White et al. ( 2016 ) Obesity (children) Fruit juice
Fattore et al. ( 2017 ) Blood lipids, blood pressure (adults) Free sugars (fructose, sucrose and glucose)
Gibson ( 2008 ) Obesity (adults and children) Sugar‐sweetened soft drinks (SSD)
Gibson et al. ( 2013 ) Blood lipids, blood pressure, glucose metabolism (adults) Sucrose
Greenwood et al. ( 2014 ) Risk of T2DM SSD
Huang et al. ( 2014 ) Risk of CVD SSBs
Imamura et al. ( 2015 ) Risk of T2DM SSB, fruit juice
Jayalath et al. ( 2014 ) Blood pressure Fructose‐containing sugar (high‐fructose corn syrup, sucrose and fructose)
Jayalath et al. ( 2015 ) Blood pressure SSBs containing free or bound fructose
Kaiser et al. ( 2013 ) Obesity (adults and children) SSBs
Kelishadi et al. ( 2014 ) Blood lipids, blood pressure, glucose metabolism Fructose
Keller and Bucher Della Torre ( 2015 ) Blood lipids, Blood pressure, glucose metabolism, risk of CVD SSBs
Kim and Je ( 2016 ) Blood pressure SSBs and artificially sweetened beverages
Ma et al. ( 2016 ) Obesity (adults and children) Fructose, glucose, SSB, HFCS
Malik et al. ( 2010 ) Risk of T2DM SSBs
Malik et al. ( 2013 ) Obesity (adults and children) SSBs
Malik et al. ( 2014 ) Blood pressure SSBs
Mattes et al. ( 2011 ) Obesity (adults and children) SSBs
Moynihan and Kelly ( 2014 ) Dental caries (adults and children) Total sugars, free sugars, added sugars, sucrose, NME sugars
Perez‐Morales et al. ( 2013 ) Obesity (children) SSBs
SACN ( 2015 ) Blood lipids, blood pressure, dental caries, glucose metabolism, obesity, risk of CVD, risk of T2DM Total carbohydrate, sugars reported as a nutrient (fructose, sucrose, lactose, glucose), table sugar and other extrinsic sugars (syrups), food format (solid vs. liquid, which includes SSBs)
Singh et al. ( 2011 ) Risk of gout (adults) SSBs, fructose
Sonestedt et al. ( 2012 ) Blood lipids, blood pressure, glucose metabolism, risk of CVD, risk of T2DM SSBs, sugars, sucrose and fructose
Te Morenga et al. ( 2013 ) Obesity (adults and children) Free sugars
Te Morenga et al. ( 2014 ) Blood lipids, blood pressure Sugar (sucrose) or free sugars
David Wang et al. ( 2014 ) Blood lipids Fructose
Wang et al. ( 2014 ) Glucose metabolism (adults) Fruit juice
Xi et al. ( 2014 ) Risk of T2DM Fruit juice
Xi et al. ( 2015 ) Blood pressure, risk of CVD SSBs
Zheng et al. ( 2015 ) Obesity (adults and children) SSBs

SSB: sugar‐sweetened beverage; NAFLD: non‐alcoholic fatty liver diseases; T2D: type 2 diabetes mellitus; CVD: cardiovascular disease; HFCS: high‐fructose corn syrup.