Table 10.

Summary of NOAELs and LOAELs identified for hazard characterisation of DAS for those farm and companion animal species for which data on relevant adverse health effects could be identified. The NOAEL/LOAEL values are reported both as doses (mg DAS/kg bw) and concentrations (mg DAS/kg feed)

Animal species	Reference point dose		Reference point concentration		Adverse effect
	NOAEL (mg DAS/kg bw per day)	LOAEL (mg DAS/kg bw per day)	NOAEL (mg DAS/ kg feed)	LOAEL (mg DAS/kg feed)
Pigs	n.d.	0.08	n.d	2.0	Oral lesions
	n.d.	0.12	n.d.	2.0	Reduced bw gain
Chicken	n.d.	0.01	n.d.	0.2	Oral lesions
	0.05	0.1	1.0	2.0	Reduced bw gain
	0.2	0.4	5.0	10.0	Reduced fertility
Laying hens	n.d.	0.054	n.d	2.0	Oral lesions
	0.33	0.60	5.0	10	Reduced bw gain
	0.60	1.01	10	20	Reduced egg production
Ducks	n.d.	0.022	n.d.	0.3	Oral lesions
Turkeys	n.d.	0.012	n.d.	0.2	Oral lesions
	0.047	0.29	0.86	4.0	Reduced bw gain
Dogs	0.031	n.d.	0.08	n.d.	Emesis
	0.016	0.031	0.04	0.08	Haematotoxicity

DAS: diacetoxyscirpenol; bw: body weight; NOAEL: no observed adverse effect level; LOAEL: lowest observed adverse effect level; n.d.: not determined,